Marketed Products Of Floating Tablets

  • Formulation and Evaluation of Floating Tablet of Captopril
  • Generic sustained release tablets of trimetazidine ...
  • Formulation and Evaluation of Gastroretentive Dosage Forms ...
  • Formulation and evaluation of glipizide floating ...
  • Importance of Floating Drug Delivery System - MarketWatch
  • Formulation and Evaluation of Floating Tablet of Captopril

    lag time (time period between placing the tablet in the medium and the floating time) method described by Rosaet al, 1994. Tablets were placed in a 100 ml beaker containing 0.01 N HCL. The time required for the tablets to rise to the surface and float was taken as the floating lag time.7, 23, 24 Evaluation of Tablets12,17 Hardness The objective of the present studies was systematic development of floating-bioadhesive gastroretentive tablets of cefuroxime axetil employing rational blend of hydrophilic polymers for attaining controlled release drug delivery. As per the QbD-based approach, the patient-centric target product profile and quality attributes of tablet were earmarked, and preliminary studies were conducted for ... tablets marketed in Kuala Lumpur. Method: The quality control parameters of five different brands of atenolol tablets were atenolol tablet assessed included uniformity of content, uniformity of weight, friability, crushing strength, disintegration and dissolution tests as well as content uniformity of the tablets. All the tablets were assessed ...

    FORMULATION AND EVALUATION OF CLARITHROMYCIN FLOATING TABLET

    Evaluation of tablets Shape of tablets Tablet dimension Thickness Hardness Friability Weight variation Test for content uniformity Tablet density Buoyancy / Floating test Swelling study Effect of hardness and Buoyance Lag time or Floating Lag time Invitro dissolution study 7. RESULT AND DISCUSSION 65-87 8. CONCLUSION 88-90 9. BIBLIOGRAPHY 91-99 Objective: The objective of this study was to develop a floating matrix tablet of Metoclopramide based on HPMC matrices and check the effect of controlled release property of the drug with marketed formulation. Method: Tablets are prepared by wet

    FORMULATION AND EVALUATION OF FLOATING TABLETS OF ...

    The prepared tablets of all the formulations were evaluated for physical characters like tablet hardness, friability, weight variation, buoyancy lag time, total floating time, assay and In-vitro drug release. better control of drug release and the drug release was similar to that of marketed product. Keyword: Theophylline, Gastro retentive floating tablets, Polymers HPMCK4M, HPMCK100M and HPMC 15cps. 1 ... Effervescent or carbon tablets are tablets which are designed to dissolve in water, and release carbon dioxide. They are products of compression of component ingredients in the form of powders into a dense mass, which is packaged in blister pack, or with a hermetically sealed package with incorporated desiccant in the cap. To use them, they are dropped into water to make a solution.

    Generic sustained release tablets of trimetazidine ...

    The values of the pharmacokinetic parameters of the prepared and marketed tablets are given in Table 6. The mean C max values for self-made sustained release tablets and marketed product were 628.17 ng/ml and 688.00 ng/ml, respectively, reached after time (T max) 2.6 h and 2.2 h, respectively. FLOATING DRUG DELIVERY SYSTEM - OMICS International Formulation and Evaluation of Dicloxacillin Sodium Floating Tablets. Murari Pavan 1 *, Prasanth VV 1, Abhishek Sharma 1, Ajay Chauhan 1, Rinku Mathappan 2, and Sam T Mathew 3. Department of Pharmaceutics, Gautham College of Pharmacy, Bangalore 560 032, Karnataka, India.

    Formulation and Evaluation of Swellable and Floating ...

    The floating lag time of marketed product is found to be 185 s, which is more compared to F12. All the parameters lie within the limits. The hardness is maintained as 9 ± 0.50 kg/cm 2 in all the formulation. The friability of all the formulations falls in the acceptable limits. Name of marketed product of ranitidine hydrochloride floating tablet? Answer. Wiki User August 05, 2012 11:45AM. ZANTAC. Related Questions. Asked in Japan in WW2, Marketing Advertising and Sales ... Thus from the studies it can be concluded that the prepared Tablets exhibited satisfactory physicochemical characteristics and all the prepared batches showed good in vitro buoyancy. Formulations showed better control of drug release and the drug release was similar to that of marketed product. Keywords: Cefexime, floating, HPMC K4M, carbopol

    Formulation and Evaluation of Effervescent Floating Tablet ...

    investigation effervescent floating tablets of different formulation were developed with an objective of achieving 24 hrs floating and drug release time and the effervescent floating tablet was compared with marketed formulation of famotidine.This approach also reduces the unwanted side effects of the drug, the tablet remain Floating delivery system of ranitidine hydrochloride was prepared using different grades of HPMC as drug release retarding polymer and sodium bicarbonate as source for carbon dioxide which helps tablets to float. Tablets were prepared by direct compression. CiteSeerX - Document Details (Isaac Councill, Lee Giles, Pradeep Teregowda): Plan: Formulation of oral gastro retentive floating tablets of Theophylline. Prologue: The primary aim of the present study is to design a sustained release gastro retentive oral dosage form using intra gastric floating as formulation strategy. Theophylline, an antiasthmatic is used as the model drug.

    Trends in floating drug delivery systems

    technological developments of FDDS including patented delivery systems and marketed products have been discussed. In addition, the pharmaceutical basis of their design, their advantages and future potential for oral controlled drug delivery are discussed. Keywords: Drug delivery systems, Gastric residence times (GRT), Floating drug delivery system (FDDS) IPC Code: F16K17/26 Introduction One ... This study was designed to develop a controlled-release floating matrix tablet and floating raft system of Mebeverine HCl (MbH) and evaluate different excipients for their floating behavior and in vitro controlled-release profiles. Oral pharmacokinetics of the optimum matrix tablet, raft system formula, and marketed Duspatalin® 200 mg retard ...

    Floating drug delivery system ppt - SlideShare

    Marketed Products of GRDDS Brand name Delivery system Drug (dose) Company name Valrelease® Floating capsule Diazepam (15mg) Hoffmann-LaRoche, USA Madopar® HBS (Prolopa® HBS) Floating, CR capsule Benserazide (25mg) and Ldopa (100mg) Roche Products, USA Liquid Gaviscon® Effervescent Floating liquid alginate preparations Al hydroxide (95 mg ... The main purpose of the study is to evaluate the quality of different marketed products of Atorvastatin calcium tablets available in the Middle East in Asir region, Kingdom of saudi Arabia, with a view to determine their interchangeability in clinical practice. Survey of the assessed Atorvastatin brands was carried out in south western cities of Saudi Arabia based on their prices.

    Development and evaluation of gastroretentive floating ...

    Tablet thickness was also used to assess the quality of tablets. The thickness of floating tablets ranged from 3.16 to 3.58 mm. Friability test of all the formulations was found satisfactory showing enough resistance to the mechanical shock and abrasion less than 1%. Drug content in all formulations was calculated and the presence of active ingredient ranged from 97 to 102%. Low density material: Polypropylene foam powder (Accurel MP 1000).Marketed product of Floating drug delivery System:-66,67,68.Sr no Brand name Drug Remark Company1 Cifran OD® Ciprofloxacin Gas generating Ranbaxy floating tablet2 Valrelease® Diazepam Floating Capsule Hoffman-LaRoche USA3 Oflin OD® Ofloxacin Gas generating Ranbaxy floating ... various marketed products and the patents filed/granted for GRRDS of antihypertensives. The GRDDS investigated include effervescent and non-effervescent floating drug delivery systems, swelling and expanding systems and bio/mucoadhesive systems. Many other systems that provided research platforms include high density systems, raft forming systems and osmotic delivery systems. In clinical ...

    Formulation and Evaluation of Gastroretentive Dosage Forms ...

    Preparation of Clarithromycin Floating Tablets . CLA 500 mg was mixed with required quantities of HPMC K4 M, Avicel ph-101 for 3–5 minutes, the blend was granulated mechanically by hand, using 2% PVP K-30 in Isopropanol as binder, the wet coherent mass was dried in hot air oven at 40°C and passed through sieve # 20, the granules were mixed with sodium bicarbonate, followed by lubrication ... Plan: Formulation of oral gastro retentive floating tablets ofTheophylline.Prologue: The primary aim of the present study is to design a sustainedrelease gastro retentive oral dosage form using intra gastric floating asformulation strategy. Theophylline, a...

    Formulation, release characteristics, and bioavailability ...

    This study was designed to develop a controlled-release floating matrix tablet and floating raft system of Mebeverine HCl (MbH) and evaluate different excipients for their floating behavior and in vitro controlled-release profiles. Oral pharmacokinetics of the optimum matrix tablet, raft system formula, and marketed Duspatalin® 200 mg ... Floating delivery system of Ranitidine hydrochloride was prepared using different grades of HPMC as drug rel retarding polymer and sodium bicarbonate as source for carbon dioxide which helps tablets to float. Tablets were prepared by direct compression. The prepared tablets were evaluated their physicochemical properties and drug release,

    Comparison of Gastro Retentive Floating Tablets of ...

    Comparison of Gastro Retentive Floating Tablets of Losartan K with Conventional Marketed Tablets Bhagyashri Chavan, Abha Doshi Abstract The present study is an attempt to increase therapeutic efficacy, reduce frequency of administration and improve patient compliance of losartan potassium by developing sustained release tablets. It was ... release. The marketed product was evaluated for the said physiochemical parameters and the in vitro release of tramadol from the developed formulation was compared with the marketed one. The marketed product is available as tablet containing tramadol hydrochloride 100 mg. MATERIALS AND METHODS Materials: Tramadol hydrochloride was The tablets with HPMCK4M and HPMCK100M floated for longer duration and had more matrix integrity as compared to formulations containing HPMC 15cps. Formulations with HPMCK100M & HPMCK4M showed better control of drug release and the drug release was similar to that of marketed product

    Formulation and evaluation of glipizide floating ...

    Floating Behavior of Tablets . The in vitro floating behavior of the tablets was studied in 500 ml preheated 0.1NHCl (pH 1.2, 37º C, no enzyme) and stirred at 50 rpm with a paddle (USP paddle method). The floating lag times (time period between placing the tablet in the medium and tablet floating) and floating durations of the tablets were ... From in vivo bioavailability studies, after oral administration of floating tablet containing 100 mg Ritonavir, the Cmax, Tmax, and AUC0–∞ of optimized gastroretentive formulation were found to be 30.11 ± 1.16µg/mL, 8.00±1.23 h and 173 ± 26.34µg*h/ml, respectively. Cmax and AUC values of optimized formulation were found to be ...

    Formulation and Evaluation of Glipizide Floating ...

    Formulation and Evaluation of Glipizide Floating-Bioadhesive Tablets Braz. Arch. Biol. Technol. v.53 n. 5: pp. 1073-1085, Sept/Oct 2010 1075 maximum rate of its absorption, then the oral bioavailability of glipizide could be improved. Based on this hypothesis, the gastric floating and bioadhesive tablets were designed in such a way The in vivo gastric retention study results indicated that the mini-tablets could retain in the stomach for more than 6.67 h. Furthermore, the AUC 0− t of the floating mini-tablets (6849.83 ± 753.80 h ng·mL −1) was significantly higher than that of marketed sustained-release tablets XATRAL®XL (4970.16 ± 924.60 h ng·mL −1). All these ...

    DESIGN AND EVALUATION OF GASTRORETENTIVE FLOATING TABLET ...

    Original Article DESIGN AND EVALUATION OF GASTRORETENTIVE FLOATING TABLET OF NIZATIDINE: A TRIAL TO IMPROVE ITS EFFICACY GEHAN BALATA 1, 2 1Department of Pharmaceutics, Faculty of Pharmacy, Zagazig University, Zagazig, Egypt, 2Department of Pharmaceutics, Faculty of Pharmacy, Umm Al-Qura University Makkah, KSA. Formulation, release characteristics, and bioavailability study of gastroretentive floating matrix tablet and floating raft system of Mebeverine HCl Mohamed A El Nabarawi,1 Mahmoud H Teaima,1 Rehab A Abd El-Monem,2 Nagla A El Nabarawy,3 Dalia A Gaber4 1Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Cairo University, Cairo, Egypt; 2Department of Pharmaceutics and ... The tablets were prepared by direct compression method and the release rate was found to decrease with proportional increase in the ratio of polymer to drug. Quetiapine fumarate has good water solubility and is absorbed well from stomach and therefore is a very good drug to be formulated into gastro retentive floating dosage form. In-vitro ...

    Formulation and Evaluation of Gastroretentive Floating ...

    height of a tablet and w is the weight of a tablet. All measurements were performed in six replicates. Floating properties of tablets The tablets were placed in a 100 ml glass beaker containing 0.1 N HCl. 1. Floating Lag Time: The time required for the tablet to rise to the surface of the medium and float was determined as floating lag time 2 ... Marketed product of metformin hcl OYes Buy Now! Best choice. Low price and best customer support! Only Quality tabs. U.S., Canada- fast shipping!

    Importance of Floating Drug Delivery System - MarketWatch

    40. Swain RP, Pendela S. Formulation and Evaluation of Gastrobilayer floating Tablets of Simvastatin as Immediate Release Layer and Atenolol as Sustained Release Layer. Indian Journal of ... to achieve desired product quality while providing OPTIMIZATION AND EVALUATION OF CLARITHROMYCIN FLOATING TABLETS USING EXPERIMENTAL MIXTURE DESIGN TIMUCIN U URLU*, U UR KARA«I«EK and ERKAN RAYAMAN Marmara University, Faculty of Pharmacy, Department of Pharmaceutical Microbiology, 34668, Haydarpasa, Istanbul, Turkey

    FORMULATION AND EVALUATION OF FLOATING TABLETS USING ...

    In the study, the concepts of gastric emptying and absorption windows and current technological developments in gastroretentive drug delivery systems were discussed including their advantages and disadvantages alongwith various evaluation techniques and marketed products for gastroretentive drug delivery. According to the authors, the ... Pelagia Research Library in-vitro release characteristics in comparison to marketed product and effect of hardness on floating lag time. MATERIALS AND METHODS Chemicals: Ciprofloxacin Hydrochloride was obtained from Karnataka Antibiotics and Pharmaceuticals Ltd., Bangalore, India. HPMC K4M, HPMC K15M were gift samples from Dr . Reddy's Laboratories

    “Formulation and Evaluation of Floating Matrix Tablet of ...

    and Evaluation of Floating Matrix Tablet of Captopril and Losartan Potassium for Treatment of Hypertension ... 1.1 Marketed Products of GRDDS 8 4.1 List of materials used 37 4.2 List of equipments used 37 4.3 Angle of repose as an indication of granule flow properties 40 4.4 Relationship between powder flow and percentage compressibility 41 4.5 Hausner’s ratio as an indication of granule ... FORMULATION AND CHARACTERIZATIOIN OF BILAYER FLOATING TABLETS OF RANITIDINE P.Dinesh Kumar*, Grace Rathnam1, C.R. Prakash, G.Saravanan2, V. Karthick and T. Panneer Selvam *Department of Pharmaceutics, Rahul Institute of Pharmaceutical Science & Research, Chirala-523157, Andhra Pradesh, India. 6.1.3 Multimedia dissolution of Ofloxacin marketed formulation In vitro dissolution study of the marketed product (ZANOCIN–OD 400mg) was carried out to compare the drug release profile with that of the formulated Ofloxacin floating tablets. The same dissolution method used for the formulations was used for the marketed formulation. In ...

    (PDF) FORMULATION AND EVALUATION OF FLOATING TABLETS OF ...

    Further, prepared floating tablets were evaluated for its in vitro release characteristic in comparison with conventional marketed tablet for 12 hrs. The data of invitro dissolution study of ... an improvement in its oral bioavailability, compared to a commercial conventional product. Conclusion: The good quality of the effervescent floating gastroretentive tablets of fexofenadine HCl developed is an indication that the approach used is suitable for the formulation of the drug for tablet and floating raft system of Mebeverine HCl (MbH) and evaluate different excipients for their floating behavior and in vitro controlled-release profiles. Oral pharmacokinetics of the optimum matrix tablet, raft system formula, and marketed Duspatalin® 200 mg retard as refer-ence were studied in beagle dogs. The optimized tablet formula ...



    Further, prepared floating tablets were evaluated for its in vitro release characteristic in comparison with conventional marketed tablet for 12 hrs. The data of invitro dissolution study of . and Evaluation of Floating Matrix Tablet of Captopril and Losartan Potassium for Treatment of Hypertension . 1.1 Marketed Products of GRDDS 8 4.1 List of materials used 37 4.2 List of equipments used 37 4.3 Angle of repose as an indication of granule flow properties 40 4.4 Relationship between powder flow and percentage compressibility 41 4.5 Hausner’s ratio as an indication of granule . The floating lag time of marketed product is found to be 185 s, which is more compared to F12. All the parameters lie within the limits. The hardness is maintained as 9 ± 0.50 kg/cm 2 in all the formulation. The friability of all the formulations falls in the acceptable limits. investigation effervescent floating tablets of different formulation were developed with an objective of achieving 24 hrs floating and drug release time and the effervescent floating tablet was compared with marketed formulation of famotidine.This approach also reduces the unwanted side effects of the drug, the tablet remain Comparison of Gastro Retentive Floating Tablets of Losartan K with Conventional Marketed Tablets Bhagyashri Chavan, Abha Doshi Abstract The present study is an attempt to increase therapeutic efficacy, reduce frequency of administration and improve patient compliance of losartan potassium by developing sustained release tablets. It was . Macbook pro ipad sync. The prepared tablets of all the formulations were evaluated for physical characters like tablet hardness, friability, weight variation, buoyancy lag time, total floating time, assay and In-vitro drug release. lag time (time period between placing the tablet in the medium and the floating time) method described by Rosaet al, 1994. Tablets were placed in a 100 ml beaker containing 0.01 N HCL. The time required for the tablets to rise to the surface and float was taken as the floating lag time.7, 23, 24 Evaluation of Tablets12,17 Hardness Tablet thickness was also used to assess the quality of tablets. The thickness of floating tablets ranged from 3.16 to 3.58 mm. Friability test of all the formulations was found satisfactory showing enough resistance to the mechanical shock and abrasion less than 1%. Drug content in all formulations was calculated and the presence of active ingredient ranged from 97 to 102%. Original Article DESIGN AND EVALUATION OF GASTRORETENTIVE FLOATING TABLET OF NIZATIDINE: A TRIAL TO IMPROVE ITS EFFICACY GEHAN BALATA 1, 2 1Department of Pharmaceutics, Faculty of Pharmacy, Zagazig University, Zagazig, Egypt, 2Department of Pharmaceutics, Faculty of Pharmacy, Umm Al-Qura University Makkah, KSA. Apple o android que es mejora. The values of the pharmacokinetic parameters of the prepared and marketed tablets are given in Table 6. The mean C max values for self-made sustained release tablets and marketed product were 628.17 ng/ml and 688.00 ng/ml, respectively, reached after time (T max) 2.6 h and 2.2 h, respectively. Groups iphone app guided ways reciter. technological developments of FDDS including patented delivery systems and marketed products have been discussed. In addition, the pharmaceutical basis of their design, their advantages and future potential for oral controlled drug delivery are discussed. Keywords: Drug delivery systems, Gastric residence times (GRT), Floating drug delivery system (FDDS) IPC Code: F16K17/26 Introduction One . Haines city walmart electronics store.

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